Have you heard of LATE Dementia? LATE is yet another unique type of deterioration that causes dementia. “Elderly adults commonly have memory and thinking problems that look a lot like Alzheimer’s disease, but they might really be suffering from a different form of dementia,” writes Amy Norton at WebMD.
LATE is the mnemonic for limbic-predominant age-related TDP-43 encephalopathy. LATE can often be confused for Alzheimer’s disease. It also causes memory loss, but its symptoms tend to progress slower than Alzheimer’s, it only shows up in adults over 80 years old and the pathology is completely different.
I began offering hypnosis for dementia in 1997, and I was excited when in 2007, Dr. Simon Duff, PhD and Dr. Dan Nightingale, PhD, published their study, Alternative Approaches to Supporting Individuals With Dementia. Their study showed the dramatic impact that hypnotherapy had in improving seven areas of quality of life:
- Immediate Memory
- Memory for Significant Events
- Activities of Daily Living
If you or a loved one have dementia or have other health challenges, Medical Hypnosis may be of benefit to you. Call (760-219-8079) or email me now. We can meet at Palm Desert Hypnosis on online worldwide. Together, no matter where you may live, we can develop a hypnosis program for you.
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Limbic-predominant age-related TDP-43 encephalopathy
LATE is a recently recognized brain disorder that mimics symptoms of Alzheimer’s disease. It was first written about in the April 30 issue of the journal Brain, by an international panel of experts who dubbed the condition limbic-predominant age-related TDP-43 encephalopathy — with the more memorable acronym, LATE.
Recent research shows that misfolded TDP-43 protein is very common in older adults. Roughly 25 percent of individuals more than 85 years of age have enough misfolded TDP-43 protein to affect their memory and/or thinking abilities.
LATE is an under-recognized condition with a very large impact on public health. The “oldest-old” are at greatest risk, and it is believed that the public health impact of LATE is at least as large as Alzheimer’s in this group.
Some people who die with what appears to be Alzheimer’s do not show the telltale signs of the disease when their brains are autopsied – namely, abnormal protein clumps known as plaques and tangles. That means their dementia symptoms did not arise from Alzheimer’s.
LATE does “mimic” Alzheimer’s. It causes memory loss and problems with thinking and reasoning that ultimately keep elderly people from being able to care for themselves.
But the LATE-affected brain looks very different from the Alzheimer’s brain.
People with LATE also frequently show a severe shrinkage in the brain’s hippocampus, a structure involved in memory and learning.
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